Louise Joy Brown, the world’s initial successful tubing baby, born in England on twenty five may1978, was one in all the trail breaking action within the history of medicine. After subsequent attainment, such a lot of babies were produced around the globe with less difficulty by the assistance of latest technology within the field of Artificial insemination. AI (Artificial Intelligence) is that the method inside the gamete is placed into the reproductive of a feminine reproductive tact for impregnating the feminine. The course is by artificial means done instead of sexual activity or natural insemination. With the technological progression the synthetic insemination became easier and reliable. Here the ovaries are aroused with gonadotropin or HMG to supply many eggs per cycle. Once the eggs reach maturity period, organic process is triggered by either endogenous LH surge or by an injection of HCG. Thirty six to forty three hours later, close to the time of ovulation, a spermatozoon sample, which is prepared, is placed into the uterine cavity via slender tubing. This treatment regime will increase the possibility of conceiving. Intrauterine Insemination (IUI) or AI is most ordinarily used for unexplained pregnancy. It’s conjointly used for couples laid low with delicate endometriosis, issues with organic process, delicate male issue physiological state and cervical infertility factor.